The article describes the results of the spread of invasive pest insects that seriously affect the vegetable-police agrocenoses across Central Fergana. During the research, it was found that Colorado potato beetle (Leptinotarsa decemlineata), tomato moth (Tuta absoluta), mulberry moth (Glyphodes pyloalis) and onion fly (Delia platura) entered as adventive species and became dominant in the valley.